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A loading dose is most useful for drugs that are eliminated from the body relatively slowly, i.e. have a long systemic half-life. Such drugs need only a low maintenance dose in order to keep the amount of the drug in the body at the appropriate therapeutic level, but this also means that, without an initial higher dose, it would take a long ...
In medicine, an indicationis a valid reason to use a certain test, medication, procedure, or surgery.[1] There can be multiple indications to use a procedure or medication.[2] An indication can commonly be confused with the term diagnosis. A diagnosis is the assessment that a particular medical condition is present while an indication is a ...
In pharmacology, the term mechanism of action ( MOA) refers to the specific biochemical interaction through which a drug substance produces its pharmacological effect. [2] A mechanism of action usually includes mention of the specific molecular targets to which the drug binds, such as an enzyme or receptor. [3]
Antiarrhythmic agents, also known as cardiac dysrhythmia medications, are a class of drugs that are used to suppress abnormally fast rhythms ( tachycardias ), such as atrial fibrillation, supraventricular tachycardia and ventricular tachycardia . Many attempts have been made to classify antiarrhythmic agents.
Labetalol. Labetalol is a medication used to treat high blood pressure and in long term management of angina. [4] [5] This includes essential hypertension, hypertensive emergencies, and hypertension of pregnancy. [5] In essential hypertension it is generally less preferred than a number of other blood pressure medications. [4]
Evidence-based medicine ( EBM) is "the conscientious, explicit and judicious use of current best evidence in making decisions about the care of individual patients. ... [It] means integrating individual clinical expertise with the best available external clinical evidence from systematic research." [1] The aim of EBM is to integrate the ...
D010600. Pharmacology is the science of drugs and medications, [ 1] including a substance's origin, composition, pharmacokinetics, pharmacodynamics, therapeutic use, and toxicology. More specifically, it is the study of the interactions that occur between a living organism and chemicals that affect normal or abnormal biochemical function. [ 2]
Antianginal. An antianginal is a drug used in the treatment of angina pectoris, a symptom of ischaemic heart disease . Myocardial ischemia arises from the dysfunction of coronary macrovascular or microvascular components, leading to a compromised supply of oxygen and nutrients to the myocardium. The underlying pathophysiological mechanisms ...
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