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Peak plasma concentrations of M2 are about 40% those of the parent drug, while plasma concentrations of M1 are, in general, less than 10% those of moxifloxacin. [ 38 ] In vitro studies with cytochrome (CYP) P450 enzymes indicate that moxifloxacin does not inhibit 80 CYP3A4, CYP2D6, CYP2C9, CYP2C19, or CYP1A2, suggesting that moxifloxacin is ...
In 1979, Alcon acquired Texas Pharmacal Company which became Dermatological Products of Texas (and is now DPT Laboratories). [10] In 1984, Alcon founded the Technical Excellence Award to promote achievements in R&D excellence and has awarded it to more than 100 recipients. The Alcon product line has expanded from pharmaceuticals to the surgical ...
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That means 95,676,260,903,887,607 primes [3] (nearly 10 17), but they were not stored. There are known formulae to evaluate the prime-counting function (the number of primes smaller than a given value) faster than computing the primes. This has been used to compute that there are 1,925,320,391,606,803,968,923 primes (roughly 2 × 10 21) smaller ...
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