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952743-07-6. PubChem CID. 11387895. KEGG. D10298. CompTox Dashboard (EPA) DTXSID20915041. Brimonidine/timolol, sold under the brand name Combigan among others, is a fixed-dose combination medication eye drop used for the treatment of glaucoma. [ 1] It is a combination of brimonidine (an α 2 adrenergic agonist) and timolol (a β adrenergic ...
Brimonidine is an α 2 agonist medication used to treat open-angle glaucoma, ocular hypertension, and rosacea. [1] [2] In rosacea it improves the redness. [2] It is used as eye drops or applied to the skin. [1] [2] Common side effects when used in the eyes include itchiness, redness, and a dry mouth. [1] Common side effects when used on the ...
Open-angle glaucoma (a condition where the aqueous humour, the watery fluid inside the eyeball, cannot drain away properly) and other causes of high pressure in the eye increase the risk of damage to the retina and the optic nerve (the nerve that sends signals from the eye to the brain). [4] This can result in serious vision loss and even ...
Timolol is a beta blocker medication used either by mouth or as eye drops. [3] [5] As eye drops it is used to treat increased pressure inside the eye such as in ocular hypertension and glaucoma. [3] By mouth it is used for high blood pressure, chest pain due to insufficient blood flow to the heart, to prevent further complications after a heart ...
Serious side effects may include allergic reactions and heart failure. [3] Use is not recommended in those with asthma, a sulfonamide allergy, or a slow heart rate. [3] [7] Dorzolamide is a carbonic anhydrase inhibitor and timolol is a beta blocker. [3] Both work by decreasing the amount of aqueous humor made by the eye. [3]
Side effects in less than 10% of people include other eye problems such as itching, foreign body sensation or dry eye, as headache or hyperpigmentation (darkening) of the skin around the eye. [ 4 ] Hyperpigmentation is an adverse effect of bimatoprost, [ 5 ] while the others are fairly common for eye drops in general.
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