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These tablets contain 35% of the administered dose in an immediate-release form and 65% in a slow-release matrix. Maximum serum concentrations are achieved between 1 and 4 hours after administration. Compared to the 250- and 500-mg immediate-release tablets, the 500-mg and 1000-mg XR tablets provide higher C max, but the 24‑hour AUCs are ...
Escitalopram. Escitalopram, sold under the brand names Lexapro and Cipralex, among others, is an antidepressant of the selective serotonin reuptake inhibitor (SSRI) class. [ 7] Escitalopram is mainly used to treat major depressive disorder and generalized anxiety disorder. [ 7] It is taken by mouth, [ 7] available commercially as an oxalate ...
Nifedipine. Nifedipine, sold under the brand name Procardia among others, is a calcium channel blocker medication used to manage angina, high blood pressure, Raynaud's phenomenon, and premature labor. [2] It is one of the treatments of choice for Prinzmetal angina. [2] It may be used to treat severe high blood pressure in pregnancy. [2]
Lisdexamfetamine. Lisdexamfetamine, sold under the brand names Vyvanse and Elvanse among others, is a stimulant medication that is used to treat attention deficit hyperactivity disorder (ADHD) in children and adults and for moderate-to-severe binge eating disorder in adults. [15] Lisdexamfetamine is taken by mouth.
Desvenlafaxine. Desvenlafaxine, sold under the brand name Pristiq among others, is a medication used to treat depression. [5] It is an antidepressant of the serotonin-norepinephrine reuptake inhibitor (SNRI) class and is taken by mouth. [5] It is recommended that the need for further treatment be occasionally reassessed. [5]
Muscarinic acetylcholine receptor antagonist. This means quetiapine is a dopamine, serotonin, and adrenergic antagonist, and a potent antihistamine with some anticholinergic properties. [ 75] Quetiapine binds strongly to serotonin receptors; the drug acts as partial agonist at 5-HT 1A receptors. [ 76]
Tapentadol. Tapentadol, brand names Nucynta among others, is a centrally acting opioid analgesic of the benzenoid class with a dual mode of action as an agonist of the μ-opioid receptor and as a norepinephrine reuptake inhibitor (NRI). [4] Analgesia occurs within 32 minutes of oral administration, and lasts for 4–6 hours.
The most common side effects [14] reported by at least 2% of patients in controlled trials of sumatriptan (25-, 50-, and 100-mg tablets) for migraine are atypical sensations (paresthesias and warm/cold sensations) reported by 4% in the placebo group and 5–6% in the sumatriptan groups, pain and other pressure sensations (including chest pain ...
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