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Moxifloxacin is an antibiotic, used to treat bacterial infections, [4] including pneumonia, conjunctivitis, endocarditis, tuberculosis, and sinusitis. [4] [5] It can be given by mouth, by injection into a vein, and as an eye drop. [5] Common side effects include diarrhea, dizziness, and headache. [4]
Norfloxacin, sold under the brand name Noroxin among others, is an antibiotic [1] [2] that belongs to the class of fluoroquinolone antibiotics. It is used to treat urinary tract infections, gynecological infections, inflammation of the prostate gland, gonorrhea and bladder infection.
Moxifloxacin 400 mg orally once daily for 7 – 14 days can be given with use of caution, if macrolide-resistant M. genitalium infection is demonstrated [9] Appropriate treatment for these individuals may require further referral to a urologist if symptoms persist after initial treatment.
Ciprofloxacin is 1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7- (1-piperazinyl)-3-quinolinecarboxylic acid. Its empirical formula is C 17 H 18 FN 3 O 3 and its molecular weight is 331.4 g/mol. It is a faintly yellowish to light yellow crystalline substance.
Levofloxacin is a third-generation fluoroquinolone, being one of the isomers of ofloxacin, which was a broader-spectrum conformationally locked analog of norfloxacin; both ofloxacin and levofloxaxin were synthesized and developed by scientists at Daiichi Seiyaku. [64]
Ofloxacin is a second-generation fluoroquinolone, being a broader-spectrum analog of norfloxacin, and was synthesized and developed by scientists at Daiichi Seiyaku. [55] [56] It was first approved for marketing in Japan in 1985, for oral administration, and Daiichi marketed it there under the brand name Tarvid. [57]
Gatifloxacin. Gatifloxacin (brand names Gatiflo, Tequin, and Zymar) is an antibiotic of the fourth-generation fluoroquinolone family, [1] that like other members of that family, inhibits the bacterial enzymes DNA gyrase and topoisomerase IV . It was patented in 1986 and approved for medical use in 1999. [2]
Bedaquiline, sold under the brand name Sirturo, is a medication used for the treatment of active tuberculosis. [ 1] Specifically, it is used to treat multi-drug-resistant tuberculosis along with other medications for tuberculosis. [ 1][ 8][ 9] It is taken by mouth. [ 3]
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