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  2. Clopidogrel - Wikipedia

    en.wikipedia.org/wiki/Clopidogrel

    Clopidogrel, sold under the brand name Plavix among others, is an antiplatelet medication used to reduce the risk of heart disease and stroke in those at high risk. [10] It is also used together with aspirin in heart attacks and following the placement of a coronary artery stent ( dual antiplatelet therapy ). [ 10 ]

  3. Prasugrel - Wikipedia

    en.wikipedia.org/wiki/Prasugrel

    Prasugrel is a member of the thienopyridine class of ADP receptor inhibitors, like ticlopidine (trade name Ticlid) and clopidogrel (trade name Plavix). These agents reduce the aggregation ("clumping") of platelets by irreversibly binding to P2Y 12 receptors. Prasugrel inhibits platelet aggregation more rapidly, more consistently, and to a ...

  4. Apotex - Wikipedia

    en.wikipedia.org/wiki/Apotex

    Apotex Inc. Apotex Inc. is a Canadian pharmaceutical corporation. [ 4] Founded in 1974 by Barry Sherman, the company is the largest producer of generic drugs in Canada, with annual sales exceeding CA$ 2.5 billion. [ 5] By 2023, Apotex employed close to 8,000 people as Canada's largest drug manufacturer, with over 300 products selling in over ...

  5. This Big Pharma Pair Parts Ways - AOL

    www.aol.com/2012/10/04/this-big-pharma-pair...

    Bristol-Myers Squibb (NYS: BMY) and Sanofi (NYS: SNY) have been through a lot together, making tens of billions of dollars from selling Plavix, Avapro, and Avalide. Most notably, there was the ...

  6. The 10 Biggest-Selling Drugs That Are About to Lose Their Patent

    www.aol.com/news/2011-02-27-top-selling-drugs...

    In 2006, generic drugmaker Apotex briefly marketed generic Plavix, but was ordered to stop until November 2011. The order was extended recently by the FDA, but Plavix's patent is set to expire on ...

  7. Antiplatelet drug - Wikipedia

    en.wikipedia.org/wiki/Antiplatelet_drug

    Antiplatelet drug. An antiplatelet drug (antiaggregant), also known as a platelet agglutination inhibitor or platelet aggregation inhibitor, is a member of a class of pharmaceuticals that decrease platelet aggregation [ 1] and inhibit thrombus formation. They are effective in the arterial circulation where classical Vitamin K antagonist ...

  8. Adenosine diphosphate receptor inhibitor - Wikipedia

    en.wikipedia.org/wiki/Adenosine_diphosphate...

    Adenosine diphosphate ( ADP) receptor inhibitors are a drug class of antiplatelet agents, used in the treatment of acute coronary syndrome (ACS) or in preventive treatment for patients who are in risk of thromboembolism, myocardial infarction or a stroke. These drugs antagonize the P2Y 12 platelet receptors and therefore prevent the binding of ...

  9. Ticagrelor - Wikipedia

    en.wikipedia.org/wiki/Ticagrelor

    When in comparison to clopidogrel, there is evidence for increased risk of bleeding. [38] The PLATO trial [39] found that ticagrelor use, in conjunction with low-dose aspirin (where tolerated), had better all-cause mortality rates than the same treatment plan with clopidogrel (4.5% vs. 5.9%) in treating people with acute coronary syndrome ...

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