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Herpes virus DNA contains a gene for a protein called ICP4, which is an important transactivator of genes associated with lytic infection in HSV-1. [47] Elements surrounding the gene for ICP4 bind a protein known as the human neuronal protein neuronal restrictive silencing factor (NRSF) or human repressor element silencing transcription factor ...
Herpes labialis does not refer to the labia of the vulva, though the origin of the word is the same. The colloquial terms for this condition ("cold sore" and "fever blister") come from the fact that herpes labialis is often triggered by fever, for example, as may occur during an upper respiratory tract infection (i.e. a cold). [12]
The annual incidence in Canada of genital herpes due to HSV-1 and HSV-2 infection is not known (for a review of HSV-1/HSV-2 prevalence and incidence studies worldwide, see Smith and Robinson 2002). As many as one in seven Canadians aged 14 to 59 may be infected with herpes simplex type 2 virus [ 89 ] and more than 90 per cent of them may be ...
Herpes simplex research includes all medical research that attempts to prevent, treat, or cure herpes, as well as fundamental research about the nature of herpes. Examples of particular herpes research include drug development , vaccines and genome editing.
Nine herpesvirus types are known to primarily infect humans, [7] at least five of which are extremely widespread among most human populations, and which cause common diseases: herpes simplex 1 and 2 (HSV-1 and HSV-2, also known as HHV-1 and HHV-2; both of which can cause orolabial and genital herpes), varicella zoster (or HHV-3; the cause of ...
Genital herpes is a herpes infection of the genitals caused by the herpes simplex virus (HSV). [1] Most people either have no or mild symptoms and thus do not know they are infected. [ 1 ] When symptoms do occur, they typically include small blisters that break open to form painful ulcers . [ 1 ]
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