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The post-mortem interval ( PMI) is the time that has elapsed since an individual's death. [1] When the time of death is not known, the interval may be estimated, and so an approximate time of death established. Postmortem interval estimations can range from hours, to days or even years depending on the type of evidence present. [2]
The Kaplan–Meier estimator is one of the most frequently used methods of survival analysis. The estimate may be useful to examine recovery rates, the probability of death, and the effectiveness of treatment. It is limited in its ability to estimate survival adjusted for covariates; parametric survival models and the Cox proportional hazards ...
Years of potential life lost. Years of potential life lost ( YPLL) or potential years of life lost ( PYLL) is an estimate of the average years a person would have lived if they had not died prematurely. [1] It is, therefore, a measure of premature mortality. As an alternative to death rates, it is a method that gives more weight to deaths that ...
Hazard ratio. In survival analysis, the hazard ratio ( HR) is the ratio of the hazard rates corresponding to the conditions characterised by two distinct levels of a treatment variable of interest. For example, in a clinical study of a drug, the treated population may die at twice the rate per unit time [clarify] of the control population.
Under de Moivre's law, the probability that (x) fails to survive to age x+t is. The force of mortality ( hazard rate or failure rate) is where f (x) is the probability density function. Under de Moivre's law, the force of mortality for a life aged x is. which has the property of an increasing failure rate with respect to age.
Life table. In actuarial science and demography, a life table (also called a mortality table or actuarial table) is a table which shows, for each age, the probability that a person of that age will die before their next birthday ("probability of death "). In other words, it represents the survivorship of people from a certain population. [1]
The doubling time is the time it takes for a population to double in size/value. It is applied to population growth, inflation, resource extraction, consumption of goods, compound interest, the volume of malignant tumours, and many other things that tend to grow over time. When the relative growth rate (not the absolute growth rate) is constant ...
The quality-adjusted life year ( QALY) is a generic measure of disease burden, including both the quality and the quantity of life lived. [1] [2] It is used in economic evaluation to assess the value of medical interventions. [1] One QALY equates to one year in perfect health. [2] QALY scores range from 1 (perfect health) to 0 (dead). [3]